![]() Damage to mammillary bodies and medial dorsal nucleus of thalamusįind Thiamine Deficiency and other Vitamins among Pixorize's visual mnemonics for the USMLE Step 1 and NBME shelf exams.High-output heart failure, dilated cardiomyopathy.Wet beriberi = cardiac problems (“blood is wet”).Confabulation, personality change, memory loss (permanent).Classic triad of confusion, ophthalmoplegia/nystagmus, ataxia.Polyneuropathy, symmetrical muscle wasting.Dry beriberi = neurologic problems (“nerves are dry”).In alcoholic or malnourished patients, give thiamine before dextrose to lower risk of precipitating acute Wernicke encephalopathy.Systemic uptake of glucose increases utilization of already low thiamine levels, leading to thiamine depletion in highly aerobic tissues (brain, heart).Wet beriberi describes cardiovascular effects of thiamine deficiency, and can include high output heart failure and dilated cardiomyopathy. ![]() Radiographic imaging of these patients typically reveals lesions at the mamillary bodies and thalamus. Korsakoff syndrome is a more severe finding that includes confabulations. Classically, Wernicke encephalopathy is characterized by confusion (encephalopathy), ataxia, and nystagmus. if this also exists, then give thiamine before glucose as glucose can precipitate the symptoms of Wernickes in. the blood, should be collected prior to thiamine administration (it is. Dry beriberi describes neurological symptoms, and includes Wernicke encephalopathy and Korsakoff syndrome. Also, Thiamine plays a key role in intracellular glucose metabolism and it is. The clinical picture of Vitamin B1 deficiency is known as beriberi, of which there are two main types: dry beriberi and wet beriberi. ![]() Summary Thiamine (Vitamin B1) Deficiency is common in alcoholics and malnourished patients. ![]()
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